AGORA Cancer Research Center

AGORA was inspired by the vision that the integration of progress in cancer research into clinical practice can be accelerated by bringing together interdisciplinary research teams of clinicians, cancer biologists, immunologists, bio-informaticians and bio-engineers. Initiated by the ISREC Foundation in 2013, the AGORA building was opened in 2018. The functioning of this translational cancer research center reflects a partnership between the Lausanne University Hospital (CHUV), the University of Lausanne (UNIL), the Swiss Federal Institute of Technology of Lausanne (EPFL), the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE).

Latest news

News

Five AGORA Members Awarded Grants by the Swiss Cancer Research Foundation

Highlighted publication

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets.

Zheng Y, Caron DP, Kim JY, (…), Stuart KD, Sims PA, Gottardo R

Nature communications – 2025 Jul 1

Events

PhD Thesis Defense | August 14th

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Events

Oncology Grand Rounds, Prof. Dominique Sprumont | August 22nd

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Events

ISREC-SCCL Symposium 2025 | September 1–4

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Events

AGORA BBQ | September 5th

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News

AGORA organization | Summer 2025

Highlighted publication

Phage display enables machine learning discovery of cancer antigen-specific TCRs.

Croce G, Lani R, Tardivon D, (…), Hebeisen M, Dunn SM, Gfeller D

Science advances – 2025 Jun 11

Highlighted publication

Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control.

Chriqui LE, Marie DN, Sifis A, (…), Joyce J, Cavin S, Perentes JY

Journal for immunotherapy of cancer – 2025 Jun 10

Highlighted publication

Trajectories of macrophage ontogeny and reprogramming in cancer

Duval F, Lourenco J, Hicham M, (…), Fournier N, Mansouri N, De Palma M

iScience – 2025 May 16

Events

AGORA Tumor Microenvironment Journal Club

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Highlighted publication

Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure

Hope HC, de Sostoa J, Ginefra, (…), Coukos G, Migliorini D, Vannini N

Nature Cancer – 2025 May 20

Past news

Latest publications

Mitochondrial control of macrophage polarity in tumors.

Kiss M, Pittet MJ

Immunity – 2025 Jul 8

Circulating tumor-associated and neoantigen-specific endogenous T cells in children treated for B-acute lymphoblastic leukemia.

Huwiler E, Thierry AC, Michaux J, (…), Bassani-Sternberg M, Harari A, Ceppi F

HemaSphere – 2025 Jul 7

A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice.

Rossari F, Alvisi G, Cusimano M, (…), Merelli I, Coltella N, Naldini L

Science translational medicine – 2025 Jul 2

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets.

Zheng Y, Caron DP, Kim JY, (…), Stuart KD, Sims PA, Gottardo R

Nature communications – 2025 Jul 1

Tumour-associated vasculature in T cell homing and immunity: opportunities for cancer therapy.

Lanitis E, Irving M, Coukos G

Nature reviews. Immunology – 2025 Jun 27