AGORA Cancer Research Center

AGORA was inspired by the vision that the integration of progress in cancer research into clinical practice can be accelerated by bringing together interdisciplinary research teams of clinicians, cancer biologists, immunologists, bio-informaticians and bio-engineers. Initiated by the ISREC Foundation in 2013, the AGORA building was opened in 2018. The functioning of this translational cancer research center reflects a partnership between the Lausanne University Hospital (CHUV), the University of Lausanne (UNIL), the Swiss Federal Institute of Technology of Lausanne (EPFL), the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE).

Latest news

Events

ISREC Foundation Minisymposium | June 16th

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Events

AGORA PRS Seminar | June 17th

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Highlighted publication

Phage display enables machine learning discovery of cancer antigen-specific TCRs.

Croce G, Lani R, Tardivon D, (…), Hebeisen M, Dunn SM, Gfeller D

Science advances – 2025 Jun 11

Highlighted publication

Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control.

Chriqui LE, Marie DN, Sifis A, (…), Joyce J, Cavin S, Perentes JY

Journal for immunotherapy of cancer – 2025 Jun 10

Events

Ludwig Distinguished Lecture, Prof. Chris Goodnow | June 19th

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Events

Oncology Grand Rounds, Post ASCO – Part Two | June 20th

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Highlighted publication

Trajectories of macrophage ontogeny and reprogramming in cancer

Duval F, Lourenco J, Hicham M, (…), Fournier N, Mansouri N, De Palma M

iScience – 2025 May 16

Events

AGORA Tumor Microenvironment Journal Club

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Highlighted publication

Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure

Hope HC, de Sostoa J, Ginefra, (…), Coukos G, Migliorini D, Vannini N

Nature Cancer – 2025 May 20

Events

ISREC-SCCL Symposium 2025 | September 1–4

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Highlighted publication

Transcriptome analysis of archived tumors by Visium, GeoMx DSP, and Chromium reveals patient heterogeneity.

Dong Y, Saglietti C, Bayard Q, (…), Gottardo R, Homicsko K, Madissoon E

Nature communications – 2025 May 12

News

Welcoming Professor Etienne Meylan to AGORA

Past news

Latest publications

Phage display enables machine learning discovery of cancer antigen-specific TCRs.

Croce G, Lani R, Tardivon D, (…), Hebeisen M, Dunn SM, Gfeller D

Science advances – 2025 Jun 11

Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control.

Chriqui LE, Marie DN, Sifis A, (…), Joyce J, Cavin S, Perentes JY

Journal for immunotherapy of cancer – 2025 Jun 10

A phase I/II trial of WT1-specific TCR gene therapy for patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell transplantation: skewing towards NK-like phenotype impairs T cell function and persistence.

Mazziotta F, Martin LE, Egan DN, (…), Milano F, Greenberg PD, Chapuis AG

Nature communications – 2025 Jun 5

Delineation of the Human Germinal Centre Immune Landscape Using Multiplex Imaging Analysis.

Georgakis S, Orfanakis M, Fenwick C, (…), Gottardo R, Pantaleo G, Petrovas C

Immunology – 2025 May 27

IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity.

Talele NP, Kumra H, Gomes-Santos IL, (…), Pittet MJ, Fukumura D, Jain RK

Journal for immunotherapy of cancer – 2025 May 24