Arber lab
Our overall goal is to develop novel targeted immunotherapies for patients with hematologic malignancies. The group develops adoptive T cell therapies with native or engineered receptors and evaluates combinatorial strategies. The objective is to efficiently t ...
Bassani lab
Our main goal is to identify clinically relevant cancer specific Human Leukocyte Antigen (HLA) ligands that will guide the development of personalized cancer immunotherapy using state of the art proteogenomics and mass-spectrometry (MS) approaches. In the clin ...
Carmona lab
We study patterns of variation across tumors to identify general principles of immune system regulation during tumor progression and response to therapy. We combine data science and computational methods development with high-throughput single-cell and spatial ...
Ciriello lab
Our laboratory integrates algorithmic design, data science, and molecular biology approaches to address relevant questions in cancer biology and therapeutics. We explore single and combinations of genetic and epigenetic alterations that emerge and are selected ...
Coukos lab
Our group focuses on engineering T cells that are associated with immune rejection in cancer. We use systems biology approaches to study the molecular states of T cells that are associated with immune deregulation or attack, either in the steady state or after ...
Dangaj lab
Our main goal is to understand tumor-intrinsic and extrinsic mechanisms that promote or dampen anti-tumor T cell immunity. To that end, my group explores the molecular states of tumor-infiltrating lymphocytes (TILs) and the tumor microenvironment (TME) at vari ...
De Palma lab
Our research program leverages new cell engineering technologies and pre-clinical trials in genetically engineered mice for advancing the conceptual understanding of the tumor microenvironment. These research efforts are poised to identify new mechanisms and v ...
Gentner lab
Our research program leverages on genetic engineering of hematopoietic stem cells (HSC) in order to develop disruptive new cell therapies against tumors. Bone marrow transplantation (BMT) is a clinically-established treatment, which allows body-wide substituti ...
Gfeller lab
Tumors form highly complex structures comprising many different cell types like cancer and immune cells. In our research, we use and develop computational biology and immuno-informatics to better understand and predict the interactions between immune and cance ...
Gottardo lab
The Translational Data Science (TDS) group focuses on developing novel computational tools, statistical methods and machine learning algorithms for the analysis of high-throughput and high-dimensional datasets generated by novel assay technologies with applica ...
Hanahan lab
We investigate tumor development and progression using genetically engineered mouse models of cancer that recapitulate important characteristics of human cancers, with strategic goals to elucidate pathogenic mechanisms underlying multi-step tumorigenesis and m ...
Harari lab
We aim to understand T-cells dynamic and correlates of efficacy in cancer patients treated with experimental immunotherapies and to develop analytical tools and pipelines for applications in immune discovery and in the development of novel strategies of cellul ...
Herrera lab
Our group is particularly interested in elucidating the molecular mechanisms by which ionizing radiation modulates tumor immunogenicity, as well as harnessing this attribute of radiation to induce therapeutic synergy with immunotherapy in pre-clinical tumor mo ...
Homicsko lab
The Homicsko laboratory aims to be at the interface between clinical and translational research. The laboratory has four main themes: 1. Decomposition of tumor and systemic immunity in human samples of real-world data and clinical studies for biomarker dev ...
Huelsken lab
The lab continues to investigate mechanistic and therapeutic implications of the cancer stem cell concept, seeking to identify targetable mechanisms of cancer progression. New approaches of immunotherapy are currently developed which aim to eradicate establish ...
Joyce lab
Our research program is focused on understanding how reciprocal communication between cancer cells and diverse immune and stromal cell types in the tumor microenvironment (TME) controls tumor initiation, progression, and metastasis, and modulates the response ...
Kandalaft lab
We work on the clinical development of personalized cancer vaccines. The aim is to improve whole tumor lysate vaccination approaches and other personalized cancer vaccine approaches by improving the dendritic cell platform and by choosing the most immunogenic ...
Merten lab
The laboratory of biomedical microfluidics (LBMM) develops novel approaches for drug discovery and personalized cancer therapy. Having a strong translational focus, we collaborate with pharma industry, foster entrepreneurship and pave the way for first clinica ...
Migliorini lab
Our laboratory aims to find new therapeutic approaches to brain cancer, and in particular to glioblastoma, which is a very aggressive form of the disease. Importantly, research over the past decades indicates that immune cells can influence the development of ...
Perentes lab
Our lab focuses on novel approaches to improve the impact of immunotherapy on malignant pleural mesothelioma and non-small cell lung cancer. We have developed clinically translatable tumor pre-treatment strategies that favor immunogenicity through cancer vascu ...
Pittet lab
Our goal is to acquire missing knowledge to find better ways to fight cancer. Our areas of expertise are immunology and immunotherapy. We are part of the Department of Pathology and Immunology at the University of Geneva, and are physically located in the AGOR ...
Precision Oncology Center (COP)
The Precision Oncology Center’s core mission is to promote personalized approaches to cancer treatment based on real-world data (RWD) collected for the entire population of past patients. We are particularly active in the following focus areas: 1) Provide a ...
Schottelius lab
The Translational Radiopharmaceutical Sciences (TRS) Lab focuses on the design, synthesis and preclinical characterization of novel radiolabeled molecules ("tracers") for non-invasive imaging of various biological processes in the human body. On the one hand, ...
Simon/Tolstonog lab
Treatment strategies for head and neck cancers include surgery, radiotherapy, chemotherapy and immunotherapy. For many patients, the curative effect of these treatments is limited and recurrence or metastasis may occur. Our laboratory studies the concept of cl ...
The Patient Lab
The Patient Lab aims to ensure the inclusion of patient and public partners in cancer research for the development of healthcare systems that respond to today’s and tomorrow’s needs and challenges. Our objective is to support researchers and patient/public ...
Waszak lab
The Laboratory of Computational Neuro-Oncology studies the genetic and molecular architecture of pediatric brain tumours, develops novel technologies for rapid and longitudinal diagnostics in pediatric neuro-oncology, and studies the evolution of pediatric gli ...