Arber lab

Our overall goal is to develop novel targeted immunotherapies for patients with hematologic malignancies. The group develops adoptive T cell therapies with native or engineered receptors and evaluates combinatorial strategies. The objective is to efficiently t ...

Bassani lab

Our main goal is to identify clinically relevant cancer specific Human Leukocyte Antigen (HLA) ligands that will guide the development of personalized cancer immunotherapy using state of the art proteogenomics and mass-spectrometry (MS) approaches. In the clin ...

Carmona lab

Working at the crossroads of data science, single-cell multi-omics, and cancer immunology, our lab develops and applies computational methods to understand how our immune system responds to cancer and to identify new therapeutic targets and biomarkers. Our gro ...

Ciriello lab

Our laboratory integrates algorithmic design, data science, and molecular biology approaches to address relevant questions in cancer biology and therapeutics. We explore single and combinations of genetic and epigenetic alterations that emerge and are selected ...

Coukos lab

Our group focuses on engineering T cells that are associated with immune rejection in cancer. We use systems biology approaches to study the molecular states of T cells that are associated with immune deregulation or attack, either in the steady state or after ...

Dangaj lab

Our main goal is to understand tumor-intrinsic and extrinsic mechanisms that promote or dampen anti-tumor T cell immunity. To that end, my group explores the molecular states of tumor-infiltrating lymphocytes (TILs) and the tumor microenvironment (TME) at vari ...

De Palma lab

Our research program leverages new cell engineering technologies and pre-clinical trials in genetically engineered mice for advancing the conceptual understanding of the tumor microenvironment. These research efforts are poised to identify new mechanisms and v ...

Dietrich lab

The Laboratory of Tumor Immunology, headed by Prof. Pierre-Yves Dietrich has been active for many years in glioma immunology. In the last decade, our group contributed to the understanding of important new concepts in the field of brain tumor immunology and in ...

Gentner lab

Our research program leverages on genetic engineering of hematopoietic stem cells (HSC) in order to develop disruptive new cell therapies against tumors. Bone marrow transplantation (BMT) is a clinically-established treatment, which allows body-wide substituti ...

Gfeller lab

Tumors form highly complex structures comprising many different cell types like cancer and immune cells. In our research, we use and develop computational biology and immuno-informatics to better understand and predict the interactions between immune and cance ...

Gottardo lab

The Translational Data Science (TDS) group focuses on developing novel computational tools, statistical methods and machine learning algorithms for the analysis of high-throughput and high-dimensional datasets generated by novel assay technologies with applica ...

Hanahan lab

We investigate tumor development and progression using genetically engineered mouse models of cancer that recapitulate important characteristics of human cancers, with strategic goals to elucidate pathogenic mechanisms underlying multi-step tumorigenesis and m ...

Harari lab

We aim to understand T-cells dynamic and correlates of efficacy in cancer patients treated with experimental immunotherapies and to develop analytical tools and pipelines for applications in immune discovery and in the development of novel strategies of cellul ...

Herrera lab

Our group is particularly interested in elucidating the molecular mechanisms by which ionizing radiation modulates tumor immunogenicity, as well as harnessing this attribute of radiation to induce therapeutic synergy with immunotherapy in pre-clinical tumor mo ...

Huelsken lab

The lab continues to investigate mechanistic and therapeutic implications of the cancer stem cell concept, seeking to identify targetable mechanisms of cancer progression. New approaches of immunotherapy are currently developed which aim to eradicate establish ...

Joyce lab

Our research program is focused on understanding how reciprocal communication between cancer cells and diverse immune and stromal cell types in the tumor microenvironment (TME) controls tumor initiation, progression, and metastasis, and modulates the response ...

Kandalaft lab

We work on the clinical development of personalized cancer vaccines. The aim is to improve whole tumor lysate vaccination approaches and other personalized cancer vaccine approaches by improving the dendritic cell platform and by choosing the most immunogenic ...

Merten lab

The laboratory of biomedical microfluidics (LBMM) develops novel approaches for drug discovery and personalized cancer therapy. Having a strong translational focus, we collaborate with pharma industry, foster entrepreneurship and pave the way for first clinica ...

Migliorini lab

Our laboratory aims to find new therapeutic approaches to brain cancer, and in particular to glioblastoma, which is a very aggressive form of the disease. Importantly, research over the past decades indicates that immune cells can influence the development of ...

Perentes lab

Our lab focuses on novel approaches to improve the impact of immunotherapy on malignant pleural mesothelioma and non-small cell lung cancer. We have developed clinically translatable tumor pre-treatment strategies that favor immunogenicity through cancer vascu ...

Pittet lab

Our goal is to acquire missing knowledge to find better ways to fight cancer. Our areas of expertise are immunology and immunotherapy. We are part of the Department of Pathology and Immunology at the University of Geneva, and are physically located in the AGOR ...

Precision Oncology Center (COP)

The Precision Oncology Center’s core mission is to promote personalized approaches to cancer treatment based on real-world data (RWD) collected for the entire population of past patients. We are particularly active in the following focus areas: 1) Provide a ...

Schottelius lab

The Translational Radiopharmaceutical Sciences (TRS) Lab focuses on the design, synthesis and preclinical characterization of novel radiolabeled molecules ("tracers") for non-invasive imaging of various biological processes in the human body. On the one hand, ...

Simon/Tolstonog lab

Treatment strategies for head and neck cancers include surgery, radiotherapy, chemotherapy and immunotherapy. For many patients, the curative effect of these treatments is limited and recurrence or metastasis may occur. Our laboratory studies the concept of cl ...