Harari lab
We aim to understand T-cells dynamic and correlates of efficacy in cancer patients treated with experimental immunotherapies and to develop analytical tools and pipelines for applications in immune discovery and in the development of novel strategies of cellular therapies ...
Research projects
Please check back later to discover our ongoing projects.
Latest publications
Detection of spontaneous anti-neoepitope T-cell responses in non-metastatic bladder cancer patients.
Brochier W, Nguyen S, Cesson V, (...), Nardelli-Haefliger D, Coulie PG, Derré L
Frontiers in immunology – 2025 Nov 12
Targeting SALL4 with an HLA Class I-restricted TCR for cancer immunotherapy.
Ben Khelil M, Fredon M, Adib N, (...), Kroemer M, Borg C, Loyon R
Cancer immunology research – 2025 Oct 20
Team
Other members
Selected Publications
Advances in predicting T cell epitope recognition for cancer immunotherapy.
Gfeller D, Racle J, Harari A, Croce G
Nature cancer – 2026 Apr 16
Harnessing TCR repertoires: predictive insights and therapeutic monitoring in cancer immunotherapy.
Chiffelle J, Genolet R, Michielin O, Harari A
Immuno-oncology technology – 2025 Oct 1
Immune correlates and mechanisms of TIL therapy efficacy: current insights and knowledge gaps.
Navarro Rodrigo B, Ortiz Miranda Y, Corria-Osorio J, Coukos G, Harari A
Trends in cancer – 2025 Aug 29
Tumor-reactive T cell clonotype dynamics underlying clinical response to TIL therapy in melanoma.
Chiffelle J, Barras D, Pétremand R, (...), Dangaj Laniti D, Harari A, Coukos G
Immunity – 2024 Sep 13
Personalized cancer T-cell therapy takes the stage, mirroring vaccine success.
Chiffelle J, Harari A
The Journal of experimental medicine – 2024 Jun 11
Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms.
Pétremand R, Chiffelle J, Bobisse S, (...), Coukos G, Zoete V, Harari A
Nat Biotechnol – 2024 May 7
A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer.
Bobisse S, Bianchi V, Tanyi JL, (...), Kandalaft LE, Harari A, Coukos G
Nature Cancer – 2023 Sep 21
Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors.
Schmidt J, Chiffelle J, Perez MAS, (...), Zoete V, Coukos G, Harari A
Nature communications – 2023 Jun 6
TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs.
Genolet R, Bobisse S, Chiffelle J, (...), Speiser DE, Coukos G, Harari A
Cell reports methods – 2023 Apr 24
Sensitive identification of neoantigens and cognate TCRs in human solid tumors.
Arnaud M, Chiffelle J, Genolet R, (...), Bobisse S, Coukos G, Harari A
Nature biotechnology – 2021 Nov 15
Related news
Events
🌱 Third AGORA Sustainability Day | May 21st
Events
AGORA PRS Seminar | May 5th
Events
🌱 Second AGORA Sustainability Day | May 21st
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AGORA Scientific Platform Workshops | November 28th
Events
LabLinks: Tumor immunology and immunotherapy | November 11&12th
Events
AGORA PRS | May 7th
Events
AGORA PRS | April 30th
Events
AGORA PRS | June 20th
Events
AGORA PRS | June 6th
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